University of California San Francisco

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Minnie M. Sarwal MD, PhD

Professor of Surgery, Medicine, Pediatrics
Professor (Adj), Stanford University, UC Berkeley
Director, Precision Transplant Medicine, UCSF
Co-Director, T32 Training Grant, Transplant Surgery, UCSF

Translational Research for Personalized Medicine

The Sarwal Lab focuses on the application of novel, high throughput technologies to harness the entire complement of genes, proteins, metabolites and antibodies, to generate new hypotheses for unraveling the underlying mechanisms of complex human diseases. Much of the work focuses on human organ transplantation , and the research efforts of the lab have resulted in a new understanding of the role of B cells, microRNAs, non-HLA antibodies and proteins in acute graft rejection; the prediction of chronic rejection and recurrent FSGS and new onset diabetes after transplantation (NODAT), and the identification of new drugs and drug targets for organ transplant recipients. The goal is to improve the quality of care and life of the patient and to assist the physician in improved and targeted management of the patient, such that there is reduced recipient morbidity and improved quality of life.

The Sarwal Lab focuses on the application of novel, high throughput technologies to harness the entire complement of genes, proteins, metabolites and antibodies, to generate new hypotheses for unraveling the underlying mechanisms of complex human diseases
Minnie M. Sarwal MD, Ph.D Principal Investigator, UCSF Sarwal Lab
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Research

Cystinosis and impaired autophagy/Mitophagy: Cystinosis is a rare autosomal recessive lysosomal storage disorder caused by the mutations in ...
GVHD is a clinical problem that has no predictive markers and is a source of high morbidity and ...
Although recent advances in immunosuppression therapy have enhanced short-term outcome; acute rejection remains an important risk factor for ...
We are conducting a large-scale genome-wide screening study across injury datasets in organ transplantation, using highly annotated genomic ...

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