Biography
In his research, Stock studies body mechanisms that lead to transplant rejection when the donor and recipient are not genetically identical. He also studies chimerism (a therapy to prevent transplant rejection that uses the donor's bone marrow cells) and pancreatic islet cell transplantation (a procedure that can allow people with type 1 diabetes to discontinue insulin therapy).
Stock received his medical training at the University of Minnesota, completing a surgical residency before coming to UCSF for a transplant fellowship. He joined the UCSF faculty in 1992.
Stock is an active teacher and supervises surgical residents and fellows. He is a member of numerous professional and honorary societies.
Videos
Education
| Institution | Degree | Dept or School | End Date | 
|---|---|---|---|
| University of California, San Francisco | Post-Doc Fellow/Scholar | Medicine | 1991 | 
| University of Illinois | M.D. | School of Medicine | 1982 | 
| University of California, San Francisco | Residency | 
Board Certifications
- American Board of Surgery, 1991
Awards & Honors
| Award | Conferred By | Date | 
|---|---|---|
| James IVth Fellowship Award | US Representative | 2000 | 
| Faculty Fellowship Award | American College of Surgeons | 1993 | 
| Sandoz Fellowship Award | American Society of Transplant Surgeons | 1991 | 
| Outstanding Surgical Resident Teaching Award | Department of Surgery, University of Minnesota, Minneapolis, MN | 1989 | 
| David Gaviser Award, Outstanding Surgical Research | University of Minnesota, Minneapolis, MN | 1989 | 
| Outstanding Research Award, Senior Medical Student | University of Illinois, Chicago, IL | 1982 | 
| Alpha Omega Alpha | University of Illinois, Chicago, IL | 1981 | 
| Magna Cum Laude, Honors in Biology with High Distinction | University of Illinois, Urbana, IL | 1978 | 
| Phi Beta Kappa | University of Illinois, Urbana, IL | 1978 | 
Clinical Expertise
Bile Duct Injuries
Bile Duct Strictures
Cholangiocarcinoma (Bile Duct Cancer)
Choledochal Cyst Disease
Dialysis Access
End-Stage Kidney Disease
Fulminant Hepatic Failure
Hepatocellular Carcinoma (Liver Cancer)
Hepatitis B
Hepatitis C
Kidney Transplantation
Kidney and LIver Transplantation in HIV Patients
Liver Transplantation
Living Donor Liver Transplantation
Living Donor Kidney Transplantation
Pediatric Liver Transplantation
Pediatric Kidney Transplantation
Pancreatic Islet Cell Transplantation
Pancreas Transplantation
Polycystic Kidney Disease
Polycystic Liver Disease
Portal Hypertension
Clinical Trials
- Related Conditions: Hypoparathyroidism| Start Date: | End Date:
- Pancreatic Islets and Parathyroid Gland Co-transplantation for Treatment of Type 1 Diabetes (NCT03977662)Related Conditions: Diabetes, Diabetes Type 1| Start Date: | End Date:
- Related Conditions: HIV/AIDS, Kidney Disease, Kidney Transplant, Transplants| Start Date: | End Date:
- Related Conditions: HIV/AIDS, Hepatitis C, Cirrhosis, Fibrosis, Liver Transplant, Liver Disease| Start Date: | End Date:
- Related Conditions: HIV/AIDS, Kidney Transplant, Transplants, Liver Transplant| Start Date: | End Date:
- Related Conditions: Diabetes, Diabetes Type 1| Start Date: | End Date:
- Kidney and Liver Transplantation in People With HIV (NCT00074386)Related Conditions: HIV/AIDS, Kidney Disease, Liver Disease, Liver Transplant| Start Date: | End Date:
Program Affiliations
Book Chapters
Zarinsefat A, Stock P. Islet vs. pancreas transplantation in nonuremic patients with type 1 diabetes. Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas. 2020 Jan 1; 417-423.
Stock PG, Mukhtar R, Ghersin H, Fiscalini AS, and Esserman L. Pragmatic Trials and Approaches to Transforming Care. In: Pawlik T.,Sosa J. (eds). Clinical Trials. Success in Academic Surgery. Springer, Cham. 2020 March 11; 59-76. https://doi.org/10.1007/978-3-030-35488-6_6
Locke J, Stock P. Renal Transplantation 7th Ed. Editor(s): Mulholland MW, Lillemoe KD, Doherty GM, Maier RV, Simeone DM, Unchurch Jr GR. G. Greenfield’s Surgery: Scientific Principles and Practice: Lippincott Williams and Wilkens, Philadelphia. In press.
In the News
Grants and Funding
- Filling a Void of Research (FAVOR) Training for Transplant Surgeons | NIH | 2016-08-01 - 2026-07-31 | Role: Principal Investigator
- Impact of CCR5 Blockade in HIV+ Kidney Transplant Recipients | NIH | 2015-08-19 - 2022-07-31 | Role: Principal Investigator
- Diabetes Research Center | NIH | 2002-09-01 - 2021-03-31 | Role: Co-Investigator
- Sofosbuvir and Ledipasvir in HIV/HCV Coinfected Pre and Post Liver Transplant | NIH | 2015-01-15 - 2019-12-31 | Role: Principal Investigator
- Impact of CCR5 Blockade in HIV+ Kidney Transplant Recipients | NIH | 2013-05-15 - 2015-04-30 | Role: Principal Investigator
- Solid Organ Transplantation in HIV: Multi-Site Study | NIH | 2003-08-15 - 2013-08-31 | Role: Principal Investigator
- General Clinical Research Center | NIH | 1974-12-01 - 2009-03-31 | Role: Co-Investigator
Research Narrative
During the last 3 years, the major thrust of my research and creative activities have focused in three areas, which are listed below along with related NIH and extramural funding covering the research since the last advancement (2018):
- Improving the outcomes of solid organ transplantation in people with HIV and translational studies bridging the previously distinct worlds of HIV and transplantation. Related funding during last 3 years: A) NIH U01Al118594-05 – Impact of CCR5 Blockade in HIV+ Kidney Transplant Recipients (Stock PI)(active until 07/31/2021); B) NIH U01 Hope in Action Prospective Multi-Center Trial (Stock Site PI)(active until 07/31/3021); C) NIHU01 Al152153-01 – Maximizing the success of HIV+ to HIV+ Kidney Transplantation in South Africa (Stock Co-Investigator)(active until 03/31/2025); D) NIH U01 A1115714-03 Sofusbuvir and Ledipasvir in HIV/HCV Coinfected Pre and Post Liver Transplant (Stock PI)(funding ended 12/31/19); E) American Foundation for AIDS Research (amfAR) 109119-57-RGRL – Impact of Everolimus on HIV Persistence Post Kidney or Liver Transplant (Stock PI)(funding ended 01/31/2018).
- Beta Cell Replacement strategies for the treatment of diabetes mellitus with pancreas transplantation, islet transplantation, or stem cell-derived beta cell clusters. We were funded ($11-million dollar grant) from CIRM to develop the forearm as a site for islet cell transplantation. This novel approach uses co-transplantation of islets with parathyroid tissue to facilitate engraftment – and has the potential for the development of a safe and accessible site for stem cell-derived beta cells. Related funding during last 3 years: A) California Institute for Regenerative Medicine (CIRM) – Islet and PARAthyroid Co-Transplantation for Treatment of Diabetes in Intra-Muscular Site (PARADIGM) (Stock PI) (active until 06/30/2023); B) NIH/NIDDK P30 DK063720 Diabetes Endocrinology Research Center (Stock Director of the Islet Production Core, German PI) (funding end 03/31/2020, renewal pending).
- Public Policy/Organ Allocation: During the last 3 years, I continue to have an active role in the development of national allocation policy. Based on previous experience as the Chair of both the national pancreas and kidney committees of UNOS, I have been funded as a senior investigator of the Scientific Registry of Transplant Recipients (SRTR). The SRTR is contracted by the government (HRSA) to provide analysis based on the national data registry to guide policy development. Related funding during last 3 years: HSRA 75R60220C00011 (annual funding – contract to continue thru 2025).
In addition to the public policy development guided by the SRTR, I have served as the Chair of the Ethics Committee of The Transplantation Society, which guides international policies regarding the complex ethical issues involved in transplantation (see Professional Competence below).
Pancreatic Islet Transplantation
The translational research in the field of pancreatic islets revolves around clinical trials of the safety and efficacy of islet transplantation in patients with Type I diabetes. The clinical trials are funded by the National Institutes of Health (NIH) and the Juvenile Diabetes Research Foundation (JDRF). These clinical trials focus on novel immunosuppressive strategies that utilize co-stimulatory blockade to prevent the immune response against pancreatic islets with a regimen that is not toxic to kidneys or beta cells.
Related research involves improving the techniques required for isolating pancreatic islets from the pancreas, which is being conducted in a fully compliant GMP laboratory facility. The study of the alloimmune and autoimmune response following islet transplantation will be conducted to determine the efficacy of the immunosuppressive strategies. Further translational studies will include methods of expanding the source of beta cells, using direct proliferation, as well as manipulation of precursor cells localized in the adult pancreas. We are currently funded (PI) for a translational grant from California Institute of Regenerative Medicine (CIRM) to bring embryonic stem cell-derived beta cells to a clinical trial.
Solid Organ Transplantation in People with HIV
With the advent of highly active anti-retroviral therapy (HAART), HIV has been a chronic disease. People with HIV are no longer dying from progression of HIV to AIDS, but rather as a result of end stage live disease (viral hepatitis co-infection) and kidney disease (HIV nephropathy). Our laboratory heads up the large NIH-sponsored national multicenter trial which is studying the safety and efficacy of solid organ transplantation in people with HIV. Translational research is exploring the impact of HIV on organ function and the impact of immunosuppression on the immune response against HIV and associated copathogens.
Research Interests
Induction of transplantation tolerance to block alloimmunity and recurrent autoimmunity following pancreatic islet transplantation
Safety and efficacy of solid organ transplantation in people with HIV
Research Pathways
Publications
- The potential of kidney transplantation to reduce mortality from chronic kidney disease: a global, cross-sectional, modelling study.| | PubMed PubMed
- Evolving Ethical Challenges After a Decade of Uterus Transplantation: Recommendations From the International Society of Uterus Transplantation Ethics Committee.| | PubMed PubMed
- Impact of Normothermic Machine Perfusion on Access to Liver Transplantation in Patients With Primary Hepatic Malignancies.| | PubMed PubMed
- Inflammation among kidney transplant donors with and without HIV: Multicenter HOPE in Action Consortium.| | PubMed PubMed
- Left Ventricular Ejection Fraction and Previous Cardiac Revascularization: Impact on Patient Survival, Graft Survival, and Complications in Kidney Transplant Recipients.| | PubMed PubMed
- Kaposi Sarcoma-Associated Herpesvirus Risk and Disease in Kidney Donors and Transplant Recipients with HIV in the United States.| | PubMed PubMed
- Obesity management before and after pancreas transplantation.| | PubMed PubMed
- APOL1 genotype and patient outcomes in US and South African transplant recipients with HIV who received kidneys from donors with HIV.| | PubMed PubMed
- OPTN/SRTR 2023 Annual Data Report: Pancreas.| | PubMed PubMed
- An Enhanced Role of Innate Immunity in the Immune Response After Kidney Transplant in People Living With HIV: A Transcriptomic Analysis.| | PubMed PubMed
- Implantation of autologous induced pluripotent stem cell-derived islets provides long-term insulin independence in a patient with type 1 diabetes.| | PubMed PubMed
- Transplantation: A Priority in the Healthcare Agenda.| | PubMed PubMed
- Safety of Kidney Transplantation from Donors with HIV.| | PubMed PubMed
- Gene expression-based molecular scoring of pancreas transplant rejection for a quantitative assessment of rejection severity and resistance to treatment.| | PubMed PubMed
- Long-term impact of immigration status on outcomes in pediatric kidney transplant recipients.| | PubMed PubMed
- Consent for High-Kidney Donor Profile Index Kidneys: The Responsibility of Transplant Centers to Get it Right.| | PubMed PubMed
- Transplantation in the Context of Migration and Refugees: A Summary of the DICG and TTS Ethics Committee Workshop, Buenos Aires, Argentina, September 2022.| | PubMed PubMed
- OPTN/SRTR 2022 Annual Data Report: Pancreas.| | PubMed PubMed
- Wait Time Advantage for Transplant Candidates With HIV Who Accept Kidneys From Donors With HIV Under the HOPE Act.| | PubMed PubMed
- Next Steps for Clinical Xenotransplantation in the United States.| | PubMed PubMed
- Expanding Access to Organ Transplant for People Living With HIV: Can Policy Catch Up to Outcomes Data?| | PubMed PubMed
- A Multi-Modal Approach to Islet and Pancreas Transplantation With Calcineurin-Sparing Immunosuppression Maintains Long-Term Insulin Independence in Patients With Type I Diabetes.| | PubMed PubMed
- The John S. Najarian symposium: The past, present, and future of surgery and transplantation, May 20, 2022, Minneapolis, MN.| | PubMed PubMed
- COVID-19 infection and vaccination rarely impact HLA antibody profile in waitlisted renal transplant candidates- a multicenter cohort.| | PubMed PubMed
- OPTN/SRTR 2021 Annual Data Report: Pancreas.| | PubMed PubMed
- The effect of induction immunosuppression for kidney transplant on the latent HIV reservoir.| | PubMed PubMed
- Erratum.| | PubMed PubMed
- Impact of Donor Liver Macrovesicular Steatosis on Deceased Donor Yield and Posttransplant Outcome.| | PubMed PubMed
- Maximizing HIV Organ Policy Equity for transplant candidates with HIV.| | PubMed PubMed
- A Worldwide Survey of Activities and Practices in Clinical Islet of Langerhans Transplantation.| | PubMed PubMed
- Considerations For Use of Propensity Score Matching in Specific Patient Populations-Reply.| | PubMed PubMed
- International Survey of Clinical Monitoring Practices in Pancreas and Islet Transplantation.| | PubMed PubMed
- National Landscape of Human Immunodeficiency Virus-Positive Deceased Organ Donors in the United States.| | PubMed PubMed
- Pancreas Transplantation for Type 2 Diabetes: A Systematic Review, Critical Gaps in the Literature, and a Path Forward.| | PubMed PubMed
- Effects of Multi-stage Procurement on the Viability and Function of Human Donor Parathyroid Glands.| | PubMed PubMed
- HBV-positive and HIV-positive organs in transplantation: A clinical guide for the hepatologist.| | PubMed PubMed
- Procurement of Deceased Donor Parathyroid Glands With the Aid of Near-infrared Autofluorescence Imaging.| | PubMed PubMed
- Long-term Outcomes Following Kidney and Liver Transplant in Recipients With HIV.| | PubMed PubMed
- OPTN/SRTR 2020 Annual Data Report: Pancreas.| | PubMed PubMed
- International Travel for Liver Transplantation: A Comprehensive Assessment of the Impact on the United States Transplant System.| | PubMed PubMed
- Advantages and Limitations of Clinical Scores for Donation After Circulatory Death Liver Transplantation.| | PubMed PubMed
- COVID-19 Vaccination in Kidney Transplant Recipients: An Ounce Pre-Transplant is Worth a Pound Post-Transplant.| | PubMed PubMed
- HOPE in action: A prospective multicenter pilot study of liver transplantation from donors with HIV to recipients with HIV.| | PubMed PubMed
- Ethical review of COVID-19 vaccination requirements for transplant center staff and patients.| | PubMed PubMed
- Examination of the Igls Criteria for Defining Functional Outcomes of β-cell Replacement Therapy: IPITA Symposium Report.| | PubMed PubMed
- Maximizing the use of hard to place kidneys: Getting the right kidney to the right recipient at the right time.| | PubMed PubMed
- First World Consensus Conference on pancreas transplantation: Part II - recommendations.| | PubMed PubMed
- Interpreting and addressing suboptimal immune responses after COVID-19 vaccination in solid-organ transplant recipients.| | PubMed PubMed
- Kidney Transplantation in HIV-positive Patients: Current Practice and Management Strategies.| | PubMed PubMed
- Tests for the noninvasive diagnosis of kidney transplant rejection should be evaluated by kidney transplant programs.| | PubMed PubMed
- New Kidney and Pancreas Allocation Policy: Moving to a Circle as the First Unit of Allocation.| | PubMed PubMed
- COVID-19 does not impact HLA antibody profile in a series of waitlisted renal transplant candidates.| | PubMed PubMed
- Live Donor Liver Transplantation in the United States: Impact of Share 35 on Live Donor Utilization.| | PubMed PubMed
- Utility of a Simplified Iliac Artery Calcium Scoring System to Guide Perioperative Management for Renal Transplantation.| | PubMed PubMed
- The demise of islet allotransplantation in the United States: A call for an urgent regulatory update.| | PubMed PubMed
- OPTN/SRTR 2019 Annual Data Report: Pancreas.| | PubMed PubMed
- Long-term Lower Extremity and Cardiovascular Complications after Simultaneous Pancreas-Kidney Transplant.| | PubMed PubMed
- Retrospective-prospective study of safety and efficacy of sofosbuvir-based direct-acting antivirals in HIV/HCV-coinfected participants with decompensated liver disease pre- or post-liver transplant.| | PubMed PubMed
- Metastatic Donor-derived Malignancies Following Simultaneous Pancreas-kidney Transplant: Three Case Reports and Management Strategies.| | PubMed PubMed
- COVID-19 and Abdominal Transplant: A Stepwise Approach to Practice During Pandemic Conditions.| | PubMed PubMed
- How COVID-19 inspired surgical residents to rethink educational programs.| | PubMed PubMed
- Impact of Sarcopenia on Simultaneous Pancreas and Kidney Transplantation Outcomes: A Retrospective Observational Cohort Study.| | PubMed PubMed
- Everolimus, an mTORC1/2 inhibitor, in ART-suppressed individuals who received solid organ transplantation: A prospective study.| | PubMed PubMed
- Phase 3 trial of human islet-after-kidney transplantation in type 1 diabetes.| | PubMed PubMed
- A prospective multicenter pilot study of HIV-positive deceased donor to HIV-positive recipient kidney transplantation: HOPE in action.| | PubMed PubMed
- Avoidance of CNI and steroids using belatacept-Results of the Clinical Trials in Organ Transplantation 16 trial.| | PubMed PubMed
- Ethical Issues in the COVID Era: Doing the Right Thing Depends on Location, Resources, and Disease Burden.| | PubMed PubMed
- A Virtual Crossmatch-based Strategy Facilitates Sharing of Deceased Donor Kidneys for Highly Sensitized Recipients.| | PubMed PubMed
- Inferior Long-Term Graft Survival of Suboptimal Kidneys After Living Donor Kidney Transplantation.| | PubMed PubMed
- Coronavirus disease 2019: Utilizing an ethical framework for rationing absolutely scarce health-care resources in transplant allocation decisions.| | PubMed PubMed
- Challenges of calcineurin inhibitor withdrawal following combined pancreas and kidney transplantation: Results of a prospective, randomized clinical trial.| | PubMed PubMed
- Long-term follow-up of beta cell replacement therapy in 10 HIV-infected patients with renal failure secondary to type 1 diabetes mellitus.| | PubMed PubMed
- Frailty Is Associated With Increased Rates of Acute Cellular Rejection Within 3 Months After Liver Transplantation.| | PubMed PubMed
- OPTN/SRTR 2018 Annual Data Report: Pancreas.| | PubMed PubMed
- Organs From Executed People Are Not a Source of Scientific Discovery.| | PubMed PubMed
- OPTN/SRTR 2017 Annual Data Report: Pancreas.| | PubMed PubMed
- Oxygen Perfusion (Persufflation) of Human Pancreata Enhances Insulin Secretion and Attenuates Islet Proinflammatory Signaling.| | PubMed PubMed
- Global Surgery: Effective Involvement of US Academic Surgery: Report of the American Surgical Association Working Group on Global Surgery.| | PubMed PubMed
- Defining Outcomes for β-cell Replacement Therapy in the Treatment of Diabetes: A Consensus Report on the Igls Criteria From the IPITA/EPITA Opinion Leaders Workshop.| | PubMed PubMed
- Organs from deceased donors with false-positive HIV screening tests: An unexpected benefit of the HOPE act.| | PubMed PubMed
- Inferior long-term graft survival after end-to-side reconstruction for two renal arteries in living donor renal transplantation.| | PubMed PubMed
- Stem Cell Therapies for Treating Diabetes: Progress and Remaining Challenges.| | PubMed PubMed
- Defining outcomes for β-cell replacement therapy in the treatment of diabetes: a consensus report on the Igls criteria from the IPITA/EPITA opinion leaders workshop.| | PubMed PubMed
- Defining outcomes for beta cell replacement therapy: a work in progress.| | PubMed PubMed
- β Cell Replacement Therapy: The Next 10 Years.| | PubMed PubMed
- OPTN/SRTR 2016 Annual Data Report: Pancreas.| | PubMed PubMed
- Strengths and weaknesses of using SRTR data to shape the management of the HIV-infected kidney transplant recipient.| | PubMed PubMed
- Splenic Vein Thrombosis Following Pancreas Transplantation: Identification of Factors That Support Conservative Management.| | PubMed PubMed
- Lessons Learned: Early Termination of a Randomized Trial of Calcineurin Inhibitor and Corticosteroid Avoidance Using Belatacept.| | PubMed PubMed
- Clinical Trials for Immunosuppression in Transplantation: The Case for Reform and Change in Direction.| | PubMed PubMed
- Erratum. National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities. Diabetes 2016;65:3418-3428.| | PubMed PubMed
- Pancreas-After-Islet Transplantation in Nonuremic Type 1 Diabetes: A Strategy for Restoring Durable Insulin Independence.| | PubMed PubMed
- Hemophilia Liver Transplantation Observational Study.| | PubMed PubMed
- Reply to Comment on the Article "OPTN/SRTR 2015 Annual Data Report: Pancreas".| | PubMed PubMed
- Canadian Laws Are on Target-But Is the Transplant Community?| | PubMed PubMed
- Opportunities and Challenges for Kidney Donation from and to HIV-Positive Individuals.| | PubMed PubMed
- OPTN/SRTR 2015 Annual Data Report: Early effects of the new kidney allocation system.| | PubMed PubMed
- OPTN/SRTR 2015 Annual Data Report: Pancreas.| | PubMed PubMed
- Strategies to improve outcomes for hepatitis C virus/human immunodeficiency virus coinfected liver transplant candidates.| | PubMed PubMed
- Why do we have the kidney allocation system we have today? A history of the 2014 kidney allocation system.| | PubMed PubMed
- Key donor factors associated with graft loss among liver transplant recipients with human immunodeficiency virus.| | PubMed PubMed
- Current outcomes in islet versus solid organ pancreas transplant for β-cell replacement in type 1 diabetes.| | PubMed PubMed
- National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities.| | PubMed PubMed
- The Effect of Water and Confinement on Self-Assembly of Imidazolium Based Ionic Liquids at Mica Interfaces.| | PubMed PubMed
- Executive Summary of IPITA-TTS Opinion Leaders Report on the Future of β-Cell Replacement.| | PubMed PubMed
- Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia.| | PubMed PubMed
- A Path to Insulin Independence: "The End of the Beginning".| | PubMed PubMed
- Liver transplant alone without kidney transplant for fibrinogen Aα-chain (AFib) renal amyloidosis.| | PubMed PubMed
- Effect of Immigration Status on Outcomes in Pediatric Kidney Transplant Recipients.| | PubMed PubMed
- Report from IPITA-TTS Opinion Leaders Meeting on the Future of β-Cell Replacement.| | PubMed PubMed
- Survival in HIV-positive transplant recipients compared with transplant candidates and with HIV-negative controls.| | PubMed PubMed
- US Findings in Patients at Risk for Pancreas Transplant Failure.| | PubMed PubMed
- A Comparative Analysis of the Safety, Efficacy, and Cost of Islet Versus Pancreas Transplantation in Nonuremic Patients With Type 1 Diabetes.| | PubMed PubMed
- Liver Retransplantation in Patients With HIV-1 Infection: An International Multicenter Cohort Study.| | PubMed PubMed
- A Source of Treatment for Those Who Were (Almost) Lost: Human Immunodeficiency Virus-Positive to Human Immunodeficiency Virus-Positive Kidney Transplantation-Results at 3 to 5 Years.| | PubMed PubMed
- Immunologic Predictors of Liver Transplantation Outcomes in HIV-HCV Co-Infected Persons.| | PubMed PubMed
- Management of the Potential Organ Donor in the ICU: Society of Critical Care Medicine/American College of Chest Physicians/Association of Organ Procurement Organizations Consensus Statement.| | PubMed PubMed
- Human immunodeficiency virus and liver transplantation: Hepatitis C is the last hurdle.| | PubMed PubMed
- Delayed hepatocellular carcinoma model for end-stage liver disease exception score improves disparity in access to liver transplant in the United States.| | PubMed PubMed
- Outcome and management of HCV/HIV coinfection pre- and post-liver transplantation. A 2015 update.| | PubMed PubMed
- Clinical practice guideline for the management of chronic kidney disease in patients infected with HIV: 2014 update by the HIV Medicine Association of the Infectious Diseases Society of America.| | PubMed PubMed
- Management of hepatitis C in kidney transplant patients: on the cusp of change.| | PubMed PubMed
- Failure to achieve normal metabolic response in non-obese diabetic mice and streptozotocin-induced diabetic mice after transplantation of primary murine hepatocytes electroporated with the human proinsulin gene (p3MTChins).| | PubMed PubMed
- Human islet viability and function is maintained during high-density shipment in silicone rubber membrane vessels.| | PubMed PubMed
- Survival of recipients of livers from donation after circulatory death who are relisted and undergo retransplant for graft failure.| | PubMed PubMed
- Reduction of HIV persistence following transplantation in HIV-infected kidney transplant recipients.| | PubMed PubMed
- Best single time point correlations with AUC for cyclosporine and tacrolimus in HIV-infected kidney and liver transplant recipients.| | PubMed PubMed
- Peginterferon and ribavirin for treatment of recurrent hepatitis C disease in HCV-HIV coinfected liver transplant recipients.| | PubMed PubMed
- Vitamin D status of human immunodeficiency virus-positive patients with advanced liver disease enrolled in the solid organ transplantation in HIV: multi-site study.| | PubMed PubMed
- Kidney infection with HIV-1 following kidney transplantation.| | PubMed PubMed
- Changes in clearance, volume and bioavailability of immunosuppressants when given with HAART in HIV-1 infected liver and kidney transplant recipients.| | PubMed PubMed
- Solid organ transplants in HIV-infected patients.| | PubMed PubMed
- Combined pancreatic islet and kidney transplantation in a child with unstable type 1 diabetes and end-stage renal disease.| | PubMed PubMed
- Chronic kidney disease after liver transplantation in human immunodeficiency virus/hepatitis C virus-coinfected recipients versus human immunodeficiency virus-infected recipients without hepatitis C virus: results from the National Institutes of Health mu| | PubMed PubMed
- Isolation and hepatocyte differentiation of mesenchymal stem cells from porcine bone marrow--"surgical waste" as a novel MSC source.| | PubMed PubMed
- Perspectives on liver and kidney transplantation in the human immunodeficiency virus-infected patient.| | PubMed PubMed
- Optimizing the program-specific reporting of pancreas transplant outcomes.| | PubMed PubMed
- Phenotypic analysis of NS5A variant from liver transplant patient with increased cyclosporine susceptibility.| | PubMed PubMed
- OPTN/SRTR 2011 Annual Data Report: liver.| | PubMed PubMed
- OPTN/SRTR 2011 Annual Data Report: pancreas.| | PubMed PubMed
- Kidney, pancreas and liver allocation and distribution in the United States.| | PubMed PubMed
- Malignancy in the HIV-infected patients undergoing liver and kidney transplantation.| | PubMed PubMed
- Surgical complications in 275 HIV-infected liver and/or kidney transplantation recipients.| | PubMed PubMed
- Liver transplant outcomes in HIV+ haemophilic men.| | PubMed PubMed
- Liver transplantation in HIV patients.| | PubMed PubMed
- Improvement in outcomes of clinical islet transplantation: 1999-2010.| | PubMed PubMed
- Outcomes of liver transplant recipients with hepatitis C and human immunodeficiency virus coinfection.| | PubMed PubMed
- Development of organ-specific donor risk indices.| | PubMed PubMed
- The Effect of HLA-DR Matching on Pediatric Kidney Transplantation-Reply.| | PubMed PubMed
- HLA-DR matching in organ allocation: balance between waiting time and rejection in pediatric kidney transplantation.| | PubMed PubMed
- The risk and opportunity of homeostatic repopulation.| | PubMed PubMed
- Transplant surgery fellow perceptions about training and the ensuing job market-are the right number of surgeons being trained?| | PubMed PubMed
- Islet transplantation in type 1 diabetic patients using calcineurin inhibitor-free immunosuppressive protocols based on T-cell adhesion or costimulation blockade.| | PubMed PubMed
- Outcomes of kidney transplantation in HIV-infected recipients.| | PubMed PubMed
- An analysis of the lack of donor pancreas utilization from younger adult organ donors.| | PubMed PubMed
- Role of PD-L1 and PD-L2 in allergic diseases and asthma.| | PubMed PubMed
- Islet transplantation in type 1 diabetics using an immunosuppressive protocol based on the anti-LFA-1 antibody efalizumab.| | PubMed PubMed
- Virologic and clinical outcomes of hepatitis B virus infection in HIV-HBV coinfected transplant recipients.| | PubMed PubMed
- Clinical islet transplantation at the University of California, San Francisco.| | PubMed PubMed
- Kidney transplantation at UCSF: 8,300 transplants and onward.| | PubMed PubMed
- Long-term survival and renal transplantation in a monozygotic twin with cloacal dysgenesis sequence.| | PubMed PubMed
- Solid organ transplantation in the HIV-infected patient.| | PubMed PubMed
- Liver and kidney transplantation in HIV-infected patients.| | PubMed PubMed
- Renal transplantation in patients with HIV.| | PubMed PubMed
- MELD score is an important predictor of pretransplantation mortality in HIV-infected liver transplant candidates.| | PubMed PubMed
- Promotion of altruistic donation.| | PubMed PubMed
- Successful clinical islet isolation using a GMP-manufactured collagenase and neutral protease.| | PubMed PubMed
- PD-L1 and PD-L2 modulate airway inflammation and iNKT-cell-dependent airway hyperreactivity in opposing directions.| | PubMed PubMed
- Viable strategies to facilitate liver transplantation for human immunodeficiency virus coinfection.| | PubMed PubMed
- Balancing multiple and conflicting allocation goals: a logical path forward.| | PubMed PubMed
- Kidney and pancreas transplantation in the United States, 1998-2007: access for patients with diabetes and end-stage renal disease.| | PubMed PubMed
- Treatment-dependent loss of polyfunctional CD8+ T-cell responses in HIV-infected kidney transplant recipients is associated with herpesvirus reactivation.| | PubMed PubMed
- Predictors associated with terminal renal function in deceased organ donors in the intensive care unit.| | PubMed PubMed
- Financial issues constraining the use of pancreata recovered for islet transplantation: a white paper.| | PubMed PubMed
- Tract-based spatial statistics of diffusion tensor imaging in adults with dyslexia.| | PubMed PubMed
- Hepatic progenitor cells from adult human livers for cell transplantation.| | PubMed PubMed
- Hepatocytes derived from adult stem cells.| | PubMed PubMed
- Human albumin preserves islet mass and function better than whole serum during pretransplantation islet culture.| | PubMed PubMed
- Are HIV-infected patients candidates for liver transplantation?| | PubMed PubMed
- Liver transplantation at UCSF--a 20-year experience.| | PubMed PubMed
- HIV-infected liver and kidney transplant recipients: 1- and 3-year outcomes.| | PubMed PubMed
- Immunosuppressant pharmacokinetics and dosing modifications in HIV-1 infected liver and kidney transplant recipients.| | PubMed PubMed
- Evolving clinical strategies for transplantation in the HIV-positive recipient.| | PubMed PubMed
- T-cell co-stimulatory molecules: their role in allergic immune reactions.| | PubMed PubMed
- The rationale for the new deceased donor pancreas allocation schema.| | PubMed PubMed
- Solid organ transplantation: referral, management, and outcomes in HIV-infected patients.| | PubMed PubMed
- Solid organ transplantation is a reality for patients with HIV infection.| | PubMed PubMed
- Inadequate hepatitis B vaccination and post-exposure evaluation among transplant surgeons: prevalence, correlates, and implications.| | PubMed PubMed
- Liver transplantation in HIV-infected recipients.| | PubMed PubMed
- Outcome of patients with hepatitis B virus and human immunodeficiency virus infections referred for liver transplantation.| | PubMed PubMed
- Thymoglobulin-associated Cd4+ T-cell depletion and infection risk in HIV-infected renal transplant recipients.| | PubMed PubMed
- Liver transplantation in HIV-seropositive individuals.| | PubMed PubMed
- Antibody-mediated rejection of a pancreas allograft.| | PubMed PubMed
- End stage polycystic kidney disease: indications and timing of native nephrectomy relative to kidney transplantation.| | PubMed PubMed
- Rapid deterioration of HIV co-infected patients waiting for liver transplantation is not predicted by MELD.| | PubMed PubMed
- Pretransplant islet culture: a comparison of four serum-free media using a murine model of islet transplantation.| | PubMed PubMed
- Cyclosporine pharmacokinetics and dosing modifications in human immunodeficiency virus-infected liver and kidney transplant recipients.| | PubMed PubMed
- Determinants of transplant surgeons' willingness to provide organs to patients infected with HBV, HCV or HIV.| | PubMed PubMed
- [Comprehensive guidelines translate research findings into clinical policy for HIV-infected transplant candidates and recipients].| | PubMed PubMed
- Current status of kidney and pancreas transplantation in the United States, 1994-2003.| | PubMed PubMed
- BKV in simultaneous pancreas-kidney transplant recipients: a leading cause of renal graft loss in first 2 years post-transplant.| | PubMed PubMed
- Ethical issues in split versus whole liver transplantation.| | PubMed PubMed
- Resiquimod, a new immune response modifier from the family of imidazoquinolinamines, inhibits allergen-induced Th2 responses, airway inflammation and airway hyper-reactivity in mice.| | PubMed PubMed
- Intraoperative fluid management of living donor versus cadaveric liver transplant recipients.| | PubMed PubMed
- Experience with steroid-free maintenance immunosuppression in simultaneous pancreas-kidney transplantation.| | PubMed PubMed
- Polyomavirus-associated nephropathy in simultaneous kidney-pancreas transplant recipients: a single-center experience.| | PubMed PubMed
- Beta-cell replacement for type I diabetes.| | PubMed PubMed
- Review of transplantation in HIV patients during the HAART era.| | PubMed PubMed
- Survival of human immunodeficiency virus-infected liver transplant recipients.| | PubMed PubMed
- Excellent short-term results with steroid-free maintenance immunosuppression in low-risk simultaneous pancreas-kidney transplantation.| | PubMed PubMed
- Alterations in skeletal muscle structure are minimized with steroid withdrawal after renal transplantation.| | PubMed PubMed
- Key clinical, ethical, and policy issues in the evaluation of the safety and effectiveness of solid organ transplantation in HIV-infected patients.| | PubMed PubMed
- Kidney and liver transplantation in human immunodeficiency virus-infected patients: a pilot safety and efficacy study.| | PubMed PubMed
- Exercise capacity and muscle structure in kidney recipient and twin donor.| | PubMed PubMed
- Health-related fitness and quality of life following steroid withdrawal in renal transplant recipients.| | PubMed PubMed
- Management of lymphoceles after renal transplantation: laparoscopic versus open drainage.| | PubMed PubMed
- De novo use of sirolimus in immunosuppression regimens in kidney and kidney-pancreas transplantation at the University of California, San Francisco.| | PubMed PubMed
- Organ donation from children with meningitis.| | PubMed PubMed
- The year in review--ATC 2002.| | PubMed PubMed
- Review of solid-organ transplantation in HIV-infected patients.| | PubMed PubMed
- Targeted gene therapy with CD40Ig to induce long-term acceptance of liver allografts.| | PubMed PubMed
- Solid organ transplantation in HIV-infected individuals.| | PubMed PubMed
- Successful long-term outcomes using pediatric en bloc kidneys for transplantation.| | PubMed PubMed
- Solid organ transplantation in HIV-positive patients.| | PubMed PubMed
- Transplantation in the HIV+ patient.| | PubMed PubMed
- A calcineurin inhibitor-sparing regimen with sirolimus, mycophenolate mofetil, and anti-CD25 mAb provides effective immunosuppression in kidney transplant recipients with delayed or impaired graft function.| | PubMed PubMed
- Experience with the use of sirolimus in liver transplantation--use in patients for whom calcineurin inhibitors are contraindicated.| | PubMed PubMed
- The effect of age and prolonged cold ischemia times on the national allocation of cadaveric renal allografts.| | PubMed PubMed
- A non-cleavable mutant of Fas ligand does not prevent neutrophilic destruction of islet transplants.| | PubMed PubMed
- A dendritic cell line genetically modified to express CTLA4-IG as a means to prolong islet allograft survival.| | PubMed PubMed
- Flow cytometry crossmatching as a predictor of acute rejection in sensitized recipients of cadaveric renal transplants.| | PubMed PubMed
- Experience with daclizumab in liver transplantation: renal transplant dosing without calcineurin inhibitors is insufficient to prevent acute rejection in liver transplantation.| | PubMed PubMed
- Liver transplantation for autoimmune hepatitis: rejection and recurrence.| | PubMed PubMed
- Simultaneous pancreas-kidney transplantation: an overview of indications, complications, and outcomes.| | PubMed PubMed
- Hepatic artery pseudoaneurysm with hemobilia following angioplasty after liver transplantation.| | PubMed PubMed
- Suggested guidelines for the use of tacrolimus in pancreas/kidney transplantation.| | PubMed PubMed
- Risks associated with conversion of stable patients after liver transplantation to the microemulsion formulation of cyclosporine.| | PubMed PubMed
- Cardiorespiratory fitness in pancreas-kidney transplant recipients.| | PubMed PubMed
- Fas ligand expression on islets as well as multiple cell lines results in accelerated neutrophilic rejection.| | PubMed PubMed
- Increased morbidity and mortality of simultaneous pancreas-renal transplantation in patients over 49 years of age.| | PubMed PubMed
- Simultaneous islet-liver transplantation: preliminary results from the UC Islet Transplantation Consortium.| | PubMed PubMed
- Immune response and myoblasts that express Fas ligand.| | PubMed PubMed
- Evidence for primary genetic determination of heart rate regulation: chromosomal mapping of a genetic locus in the rat.| | PubMed PubMed
- Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction.| | PubMed PubMed
- In utero hematopoietic stem cell transplants prolong survival of postnatal kidney transplantation in monkeys.| | PubMed PubMed
- Re-evaluation of donor factors affecting islet isolation from human pancreas using a two-step digestion method.| | PubMed PubMed
- Clonal deletion is one mechanism responsible for tolerance in mixed hematopoietic chimeras.| | PubMed PubMed
- The Y chromosome. Epistatic and ecogenetic interactions in genetic hypertension.| | PubMed PubMed
- Decreased mortality from technical failure improves results in pediatric liver transplantation.| | PubMed PubMed
- Living related donor liver transplantation: the UCSF experience.| | PubMed PubMed
- Strategies for tolerance induction: potential applications in living donor liver transplantation.| | PubMed PubMed
- In vivo (phase I) trial and in vitro efficacy of humanized anti-Tac for the prevention of rejection in renal transplant recipients.| | PubMed PubMed
- A multicenter analysis of the first experience with FK506 for induction and rescue therapy after pancreas transplantation.| | PubMed PubMed
- Clinical islet transplantation experience of the University of California Islet Transplant Consortium.| | PubMed PubMed
- Low postoperative wound infection rates are possible following simultaneous pancreas-kidney transplantation.| | PubMed PubMed
- Long-term outcome in kidney transplant patients with hepatitis C (HCV) infection.| | PubMed PubMed
- The risk of transmission of hepatitis B from HBsAg(-), HBcAb(+), HBIgM(-) organ donors| | UCSF Research Profile
- Enhancement of islet allograft survival in mice treated with MHC class I specific F(ab')2 alloantibody.| | PubMed PubMed
- beta-2 Microglobulin gene disruption prolongs murine islet allograft survival in NOD mice.| | PubMed PubMed
- Prolongation of in vivo mouse islet allograft survival by modulation of MHC class I antigen.| | PubMed PubMed
- Major histocompatibility complex class I deficiency prolongs islet allograft survival.| | PubMed PubMed
- Nonoperative management of biliary leaks after orthotopic liver transplantation.| | PubMed PubMed
- Isolation of functional MHC class I-deficient islet cells.| | PubMed PubMed
- Standard sequential immunosuppression with Minnesota antilymphoblast globulin and cyclosporine vs FK 506: a comparison of early nephrotoxicity.| | PubMed PubMed
- Evidence for direct and indirect pathways in the generation of the alloimmune response against pancreatic islets.| | PubMed PubMed
- The alloimmune response against pancreatic islets is generated by both direct and indirect pathways.| | PubMed PubMed
- Beneficial and detrimental effects of RBC-adsorbed antilymphocyte globulin and prednisone on purified canine islet autograft and allograft function.| | PubMed PubMed
- Liver transplantation.| | PubMed PubMed
- The alloimmune response to murine islets occurs via indirect antigen presentation to LYT2+ and L3T4+ lymphocytes.| | PubMed PubMed
- Seroconversion to human immunodeficiency virus in prison inmates.| | PubMed PubMed
- Immunogenic potential of passenger leucocyte depleted murine islets in-vitro and in-vivo.| | PubMed PubMed
- Modulation of MHC class I antigen decreases pancreatic islet immunogenicity.| | PubMed PubMed
- Comparative in vitro immunogenicity of cultured murine islets and hepatocytes.| | PubMed PubMed
- Factors influencing early survival after liver transplantation.| | PubMed PubMed
- Frequency of precursor cytotoxic T lymphocytes correlates with outcome following heart-lung and pancreatic islet transplantation.| | PubMed PubMed
- Pediatric liver transplantation across ABO blood group barriers.| | PubMed PubMed
- Rapid infusion technique as a safe alternative to veno-venous bypass in orthotopic liver transplant (TX).| | PubMed PubMed
- Effect of immunodepletion of MHC class II-positive cells from pancreatic islets on generation of cytotoxic T-lymphocytes in mixed islet-lymphocyte coculture.| | PubMed PubMed
- Generation of allospecific cytolytic T-lymphocytes stimulated by pure pancreatic beta-cells in absence of Ia+ dendritic cells.| | PubMed PubMed
- Pharmacokinetics of 6-thiouric acid and 6-mercaptopurine in renal allograft recipients after oral administration of azathioprine.| | PubMed PubMed
- Infection and rejection of primary hepatic transplant in 93 consecutive patients treated with triple immunosuppressive therapy.| | PubMed PubMed
- Aplastic anemia complicating orthotopic liver transplantation for non-A, non-B hepatitis.| | PubMed PubMed
- [Comparison of the results of liver transplantation in children and adults].| | PubMed PubMed
- In vitro generated allospecific cytolytic T lymphocytes injure pancreatic islets.| | PubMed PubMed
- Cyclosporine suppresses immune-mediated pancreatic islet allograft primary nonfunction and enhances long-term functional survival.| | PubMed PubMed
- On the variability of outcome after islet allotransplantation.| | PubMed PubMed
- Pancreatic islets generate allospecific cytolytic T lymphocytes in a mixed lymphocyte-islet culture.| | PubMed PubMed
- ABO-compatible mismatching decreases 5-year actuarial graft survival after renal transplantation.| | PubMed PubMed
- Functional and phenotypical characterization of activated T cells from intra-articular sites in inflammatory joint diseases. Possible modulation of the CD3 antigen.| | PubMed PubMed
- Mixed islet-lymphocyte culture as a model for pancreatic islet immunogenicity and cell-mediated immune injury.| | PubMed PubMed
- Pediatric liver transplantation using combination immunosuppressive therapy.| | PubMed PubMed
- Hepatitis-associated aplastic anemia after liver transplantation.| | PubMed PubMed
- Renal subcapsular versus portal vein site for islet transplantation in mice.| | PubMed PubMed
- Detrimental effect of ABO mismatching in renal transplantation.| | PubMed PubMed
- Permanent acceptance of islet allografts in mice is not associated with immunologic tolerance.| | PubMed PubMed
- Plasma amino acid clearance predicts hepatic recovery after normothermic anoxia and cold preservation.| | PubMed PubMed
- Prognostic perioperative factors predicting the outcome of liver transplantation.| | PubMed PubMed
- Use of triple therapy and percutaneous needle biopsy to minimize graft failure following liver transplantation.| | PubMed PubMed
- Intraarticular T lymphocytes in monoarticular and oligoarticular inflammatory joint diseases. Normal subset distribution and less numbers of activated T cells indicate major differences as compared to rheumatoid arthritis.| | PubMed PubMed
 
    